Publications Scientifiques

La reconnaissance des contributions de la plateforme de microscopie photonique de la faculté de médecine dans vos publications est grandement appréciée.
La mention des équipements que vous avez utilisés dans la section Matériels et Méthodes démontre la contribution de la plateforme à la communauté universitaire et permet d'évaluer l'impact de chaque équipement sur l'infrastructure de recherche.

Freely Behaving Mice Can Brake and Turn During Optogenetic Stimulation of the Mesencephalic Locomotor Region.
van der Zouwen CI, Boutin J, Fougère M, Flaive A, Vivancos M, Santuz A, Akay T, Sarret P, Ryczko D.
Front Neural Circuits. 2021 Apr 9;15:639900. doi: 10.3389/fncir.2021.639900. eCollection 2021.

Cardiomyocyte-specific Srsf3 deletion reveals a mitochondrial regulatory role.
Dumont AA, Dumont L, Zhou D, Giguère H, Pileggi C, Harper ME, Blondin DP, Scott MS, Auger-Messier M.
FASEB J. 2021 May;35(5):e21544. doi: 10.1096/fj.202002293RR.

The Chicken Chorioallantoic Membrane Tumor Assay as a Relevant In Vivo Model to Study the Impact of Hypoxia on Tumor Progression and Metastasis.
Harper K, Yatsyna A, Charbonneau M, Brochu-Gaudreau K, Perreault A, Jeldres C, McDonald PP, Dubois CM.
Cancers (Basel). 2021 Mar 4;13(5):1093. doi: 10.3390/cancers13051093.

Mechanistic insights into the role of the chemokine CCL2/CCR2 axis in dorsal root ganglia to peripheral inflammation and pain hypersensitivity.
Dansereau MA, Midavaine É, Bégin-Lavallée V, Belkouch M, Beaudet N, Longpré JM, Mélik-Parsadaniantz S, Sarret P.J
Neuroinflammation. 2021 Mar 23;18(1):79. doi: 10.1186/s12974-021-02125-y.

The expression of P2Y6 receptor promotes the quality of mucus in colitic mice.
Placet M, Molle CM, Arguin G, Geha S, Gendron FP.
FEBS J. 2021 Mar 13. doi: 10.1111/febs.15819. Online ahead of print.

JAK-STAT Pathway Inhibition Partially Restores Intestinal Homeostasis in Hdac1- and Hdac2-Intestinal Epithelial Cell-Deficient Mice.
Gonneaud A, Turgeon N, Boisvert FM, Boudreau F, Asselin C.
Cells. 2021 Jan 23;10(2):224. doi: 10.3390/cells10020224.

Potentiation of B2 receptor signaling by AltB2R, a newly identified alternative protein encoded in the human bradykinin B2 receptor gene.
Gagnon M, Savard M, Jacques JF, Bkaily G, Geha S, Roucou X, Gobeil F.
J Biol Chem. 2021 Jan 23;296:100329. doi: 10.1016/j.jbc.2021.100329. Online ahead of print.

RabGAP TBC1D25 is involved in human osteoclast activity.
Roy M, Stephens E, Bouhour S, Roux S.
Eur J Cell Biol. 2021 Apr;100(3):151145. doi: 10.1016/j.ejcb.2020.151145. Epub 2020 Dec 11.

S100ß-mediated astroglial control of firing and input processing in layer 5 pyramidal neurons of the mouse visual cortex.
Ryczko D, Hanini-Daoud M, Condamine S, Bréant BJB, Fougère M, Araya R, Kolta A.
J Physiol. 2021 Jan;599(2):677-707. doi: 10.1113/JP280501. Epub 2020 Dec 18.

The FUS gene is dual-coding with both proteins contributing to FUS-mediated toxicity.
Brunet MA, Jacques JF, Nassari S, Tyzack GE, McGoldrick P, Zinman L, Jean S, Robertson J, Patani R, Roucou X.
EMBO Rep. 2021 Jan 7;22(1):e50640. doi: 10.15252/embr.202050640. Epub 2020 Nov 23.

Loss of interleukin-17 receptor D promotes chronic inflammation-associated tumorigenesis.
Girondel C, Lévesque K, Langlois MJ, Pasquin S, Saba-El-Leil MK, Rivard N, Friesel R, Servant MJ, Gauchat JF, Lesage S, Meloche S.
Oncogene. 2021 Jan;40(2):452-464. doi: 10.1038/s41388-020-01540-4. Epub 2020 Nov 11.

Integrative characterization of the near-minimal bacterium Mesoplasma florum.
Matteau D, Lachance JC, Grenier F, Gauthier S, Daubenspeck JM, Dybvig K, Garneau D, Knight TF, Jacques PÉ, Rodrigue S.
Mol Syst Biol. 2020 Dec;16(12):e9844. doi: 10.15252/msb.20209844.

A Novel Proteomic Method Reveals NLS Tagging of T-DM1 Contravenes Classical Nuclear Transport in a Model of HER2-Positive Breast Cancer.
Lacasse V, Beaudoin S, Jean S, Leyton JV.
Mol Ther Methods Clin Dev. 2020 Sep 1;19:99-119. doi: 10.1016/j.omtm.2020.08.016. eCollection 2020 Dec 11.

Pharmacological Modulation of Blood-Brain Barrier Permeability by Kinin Analogs in Normal and Pathologic Conditions.
Sikpa D, Whittingstall L, Savard M, Lebel R, Côté J, McManus S, Chemtob S, Fortin D, Lepage M, Gobeil F.
Pharmaceuticals (Basel). 2020 Sep 29;13(10):279. doi: 10.3390/ph13100279.

The Hippo Pathway Effector YAP1 Regulates Intestinal Epithelial Cell Differentiation.
Fallah S, Beaulieu JF.
Cells. 2020 Aug 13;9(8):1895. doi: 10.3390/cells9081895.

Osteoclast signaling-targeting miR-146a-3p and miR-155-5p are downregulated in Paget's disease of bone.
Stephens E, Roy M, Bisson M, Nguyen HD, Scott MS, Boire G, Bouchard L, Roux S.
Biochim Biophys Acta Mol Basis Dis. 2020 May 30;1866(10):165852.

In vivo mapping of a GPCR interactome using knockin mice.
Degrandmaison J, Abdallah K, Blais V, Génier S, Lalumière MP, Bergeron F, Cahill CM, Boulter J, Lavoie CL, Parent JL, Gendron L.
Proc Natl Acad Sci USA. 2020 Jun 9;117(23):13105-13116.

Early deficits in olfaction are associated with structural and molecular alterations in the olfactory system of a Huntington disease mouse model.
Laroche M, Lessard-Beaudoin M, Garcia-Miralles M, Kreidy C, Peachey E, Leavitt BR, Pouladi MA, Graham RK.
Hum Mol Genet. 2020 Aug 3;29(13):2134-2147.

The P2Y 6 receptor signals through Ga q /Ca 2+ /PKCa and Ga 13 /ROCK pathways to drive the formation of membrane protrusions and dictate cell migration.
Girard M, Dagenais Bellefeuille S, Eiselt É, Brouillette R, Placet M, Arguin G, Longpré JM, Sarret P, Gendron FP
J Cell Physiol. 2020 May 18.

The serotonin reuptake blocker citalopram destabilizes fictive locomotor activity in salamander axial circuits through 5-HT 1A receptors.
Flaive A, Cabelguen JM, Ryczko D.
J Neurophysiol. 2020 Jun 1;123(6):2326-2342.

Brain irradiation leads to persistent neuroinflammation and long-term neurocognitive dysfunction in a region-specific manner.
Constanzo J, Midavaine É, Fouquet J, Lepage M, Descoteaux M, Kirby K, Tremblay L, Masson-Côté L, Geha S, Longpré JM, Paquette B, Sarret P.
Prog Neuropsychopharmacol Biol Psychiatry. 2020 Aug 30;102:109954.

GGA3 interacts with L-type prostaglandin D synthase and regulates the recycling and signaling of the DP1 receptor for prostaglandin D 2 in a Rab4-dependent mechanism.
Fréchette L, Binda C, Génier S, Degrandmaison J, Boisvert M, Parent JL.
Cell Signal. 2020 Aug;72:109641.

Oncolytic vesicular stomatitis virus-based cellular vaccine improves triple-negative breast cancer outcome by enhancing natural killer and CD8 + T-cell functionality.
Niavarani SR, Lawson C, Boudaud M, Simard C, Tai LH.
J Immunother Cancer. 2020 Mar;8(1):e000465.

UBB pseudogene 4 encodes functional ubiquitin variants.
Dubois ML, Meller A, Samandi S, Brunelle M, Frion J, Brunet MA, Toupin A, Beaudoin MC, Jacques JF, Lévesque D, Scott MS, Lavigne P, Roucou X, Boisvert FM.
Nat Commun. 2020 Mar 11;11(1):1306.

Cell-penetrating pepducins targeting the neurotensin receptor type 1 relieve pain.
Brouillette RL, Besserer-Offroy E, Mona CE, Chartier M, Lavenus S, Sousbie M, Belleville K, Longpré JM, Marsault E, Grandbois M, Sarret P.
Pharmacol Res. 2020 May;155:104750.

A Novel Organoid Model of Damage and Repair Identifies HNF4a as a Critical Regulator of Intestinal Epithelial Regeneration.
Montenegro-Miranda PS, van der Meer JHM, Jones C, Meisner S, Vermeulen JLM, Koster J, Wildenberg ME, Heijmans J, Boudreau F, Ribeiro A, van den Brink GR, Muncan V.
Cell Mol Gastroenterol Hepatol. 2020;10(2):209-223. doi: 10.1016/j.jcmgh.2020.02.007. Epub 2020 Mar 5.

Human Hepatocyte Nuclear Factor 4-a Encodes Isoforms with Distinct Transcriptional Functions.
Lambert É, Babeu JP, Simoneau J, Raisch J, Lavergne L, Lévesque D, Jolibois É, Avino M, Scott MS, Boudreau F, Boisvert FM.
Mol Cell Proteomics. 2020 May;19(5):808-827. doi: 10.1074/mcp.RA119.001909. Epub 2020 Mar 2.

RPTPe promotes M2-polarized macrophage migration through ROCK2 signaling and podosome formation.
Lapointe F, Turcotte S, Roy J, Bissonnette E, Rola-Pleszczynski M, Stankova J.
J Cell Sci. 2020 Jan 21;133(5):jcs234641.

Dichotomic effects of clinically used drugs on tumor growth, bone remodeling and pain management.
Barrière DA, Midavaine É, Doré-Savard L, Kirby K, Tremblay L, Beaudoin JF, Beaudet N, Longpré JM, Lecomte R, Lepage M, Sarret P.
Sci Rep. 2019 Dec 27;9(1):20155.

L-type Prostaglandin D Synthase Regulates the Trafficking of the PGD 2 DP1 Receptor by Interacting With the GTPase Rab4.
Binda C, Génier S, Degrandmaison J, Picard S, Fréchette L, Jean S, Marsault E, Parent JL.
J Biol Chem. 2019 Nov 8;294(45):16865-16883.

Hypoxia Downregulates LPP3 and Promotes the Spatial Segregation of ATX and LPP1 During Cancer Cell Invasion.
Harper K, Brochu-Gaudreau K, Saucier C, Dubois CM.
Cancers (Basel). 2019 Sep 19;11(9):1403. doi: 10.3390/cancers11091403.

p38a MAPK proximity assay reveals a regulatory mechanism of alternative splicing in cardiomyocytes.
Dumont AA, Dumont L, Berthiaume J, Auger-Messier M.
Biochim Biophys Acta Mol Cell Res. 2019 Dec;1866(12):118557.

RAB21 Interacts With TMED10 and Modulates Its Localization and Abundance.
Del Olmo T, Lacarrière-Keïta C, Normandin C, Jean D, Boisvert FM, Jean S.
Biol Open. 2019 Sep 9;8(9):bio045336.

Lipid accumulation impairs natural killer cell cytotoxicity and tumor control in the postoperative period.
Niavarani SR, Lawson C, Bakos O, Boudaud M, Batenchuk C, Rouleau S, Tai LH.
BMC Cancer. 2019 Aug 20;19(1):823.

Colorectal Cancer Cells Respond Differentially to Autophagy Inhibition in Vivo.
Lauzier A, Normandeau-Guimond J, Vaillancourt-Lavigueur V, Boivin V, Charbonneau M, Rivard N, Scott MS, Dubois CM, Jean S.
Sci Rep. 2019 Aug 5;9(1):11316.

Regulation of platelet-activating factor-mediated interleukin-6 promoter activation by the 48 kDa but not the 45 kDa isoform of protein tyrosine phosphatase non-receptor type 2.
Hamel-Côté G, Lapointe F, Véronneau S, Mayhue M, Rola-Pleszczynski M, Stankova J.
Cell Biosci. 2019 Jun 25;9:51.

Loss of PTEN signaling in Foxl1+ mesenchymal telocytes initiates spontaneous colonic neoplasia in mice.
Langlois MJ, Servant R, Reyes-Nicolas V, Jones C, Roy SA, Paquet M, Carrier JC, Rivard N, Boudreau F, Perreault N.
Cell Mol Gastroenterol Hepatol. 2019 May 27. pii: S2352-345X(19)30069-4.

Quantitative Proteomics Identifies DNA Repair as a Novel Biological Function for Hepatocyte Nuclear Factor 4α in Colorectal Cancer Cells.
Babeu JP, Wilson SD, Lambert É, Lévesque D, Boisvert FM, Boudreau F.
Cancers (Basel). 2019 May 5;11(5).

Efficacy of Combining PRP and MMP Inhibitors in Treating Moderately Damaged Tendons Ex Vivo.
Jafari L, Hassanisaber H, Savard M, Gobeil Jr F, Langelier E.
J Orthop Res. 2019 Aug;37(8):1838-1847.

Combining RNAi and Immunofluorescence Approaches to Investigate Post-endocytic Sorting of GPCRs into Multivesicular Bodies.
Li X, Rosciglione S, Laniel A, Lavoie C.
Methods Mol Biol. 2019;1947:303-322.

Monitoring the Aggregation of GPCRs by Fluorescence Microscopy.
Génier S, Degrandmaison J, Lavoie CL, Gendron L, Parent JL.
Methods Mol Biol. 2019;1947:289-302.

MURC/CAVIN-4 facilitates store-operated calcium entry in neonatal cardiomyocytes.
Malette J, Degrandmaison J, Giguère H, Berthiaume J, Frappier M, Parent JL, Auger-Messier M, Boulay G.
Biochim Biophys Acta Mol Cell Res. 2019 Aug;1866(8):1249-1259.

HDAC1 and HDAC2 independently regulate common and specific intrinsic responses in murine enteroids.
Gonneaud A, Turgeon N, Jones C, Couture C, Lévesque D, Boisvert FM, Boudreau F, Asselin C.
Sci Rep. 2019 Mar 29;9(1):5363.

HNF4α is a novel regulator of intestinal glucose-dependent insulinotropic polypeptide.
Girard R, Darsigny M, Jones C, Maloum-Rami F, Gélinas Y, Carpentier AC, Laplante M, Perreault N, Boudreau F.
Sci Rep. 2019 Mar 12;9(1):4200.

Role of Protein Tyrosine Phosphatase Epsilon (PTPε) in Leukotriene D4-Induced CXCL8 Expression.
Lapointe F, Turcotte S, Véronneau S, Rola-Pleszczynski M, Stankova J.
J Pharmacol Exp Ther. 2019 May;369(2):270-281.

Diabetes-Induced DUSP4 Reduction Promotes Podocyte Dysfunction and Progression of Diabetic Nephropathy.
Denhez B, Rousseau M, Dancosst DA, Lizotte F, Guay A, Auger-Messier M, Côté AM, Geraldes P.
Diabetes. 2019 May;68(5):1026-1039.

Olfactory bulb atrophy and caspase activation observed in the BACHD rat models of Huntington disease.
Lessard-Beaudoin M, Yu-Taeger L, Laroche M, Singer E, Riess O, Nguyen HHP, Graham RK.
Neurobiol Dis. 2019 May;125:219-231.

APEX2-mediated RAB proximity labeling identifies a role for RAB21 in clathrin-independent cargo sorting.
Del Olmo T, Lauzier A, Normandin C, Larcher R, Lecours M, Jean D, Lessard L, Steinberg F, Boisvert FM, Jean S.
EMBO Rep. 2019 Feb;20(2).

The tyrosine phosphatase Shp-2 confers resistance to colonic inflammation by driving goblet cell function and crypt regeneration.
Gagné-Sansfacon J, Langlois A, Langlois MJ, Coulombe G, Tremblay S, Vaillancourt-Lavigueur V, Qu CK, Menendez A, Rivard N.
J Pathol. 2019 Jan;247(1):135-146.

Dual-specificity phosphatase 6 deletion protects the colonic epithelium against inflammation and promotes both proliferation and tumorigenesis.
Beaudry K, Langlois MJ, Montagne A, Cagnol S, Carrier JC, Rivard N.
J Cell Physiol. 2019 May;234(5):6731-6745.

ADAP1 limits neonatal cardiomyocyte hypertrophy by reducing integrin cell surface expression.
Giguère H, Dumont AA, Berthiaume J, Oliveira V, Laberge G, Auger-Messier M.
Sci Rep. 2018 Sep 11;8(1):13605.

Functional diversity of TMPRSS6 isoforms and variants expressed in hepatocellular carcinoma cell lines.
Dion SP, Béliveau F, Morency LP, Désilets A, Najmanovich R, Leduc R.
Sci Rep. 2018 Aug 22;8(1):12562.

P1 promoter-driven HNF4α isoforms are specifically repressed by β-catenin signaling in colorectal cancer cells.
Babeu JP, Jones C, Geha S, Carrier JC, Boudreau F.
J Cell Sci. 2018 Jul 6;131(13).

The Hypoxic Tumor Microenvironment Promotes Invadopodia Formation and Metastasis through LPA1 Receptor and EGFR Cooperation.
Harper K, R Lavoie R, Charbonneau M, Brochu-Gaudreau K, Dubois CM.
Mol Cancer Res. 2018 Oct;16(10):1601-1613.

Adeno-associated virus 2/9 delivery of Cre recombinase in mouse primary afferents.
Abdallah K, Nadeau F, Bergeron F, Blouin S, Blais V, Bradbury KM, Lavoie CL, Parent JL, Gendron L.
Sci Rep. 2018 May 9;8(1):7321.

Initial Evaluation of Antibody-conjugates Modified with Viral-derived Peptides for Increasing Cellular Accumulation and Improving Tumor Targeting.
Beaudoin S, Paquette M, Fafard-Couture L, Tremblay MA, Lecomte R, Guérin B, Leyton JV.
J Vis Exp. 2018 Mar 8;(133):55440.

NLS-Cholic Acid Conjugation to IL-5Rα-Specific Antibody Improves Cellular Accumulation and In Vivo Tumor-Targeting Properties in a Bladder Cancer Model.
Paquette M, Beaudoin S, Tremblay MA, Jean S, Lopez AF, Lecomte R, Guérin B, Bentourkia M, Sabbagh R, Leyton JV.
Bioconjug Chem. 2018 Apr 18;29(4):1352-1363.

Delta opioid receptors recycle to the membrane after sorting to the degradation path.
Charfi I, Abdallah K, Gendron L, Pineyro G.
Cell Mol Life Sci. 2018 Jun;75(12):2257-2271.

Suboptimal extracellular pH values alter DNA damage response to induced double-strand breaks.
Massonneau J, Ouellet C, Lucien F, Dubois CM, Tyler J, Boissonneault G.
FEBS Open Bio. 2018 Feb 16;8(3):416-425.

The G protein-coupled P2Y₆ receptor promotes colorectal cancer tumorigenesis by inhibiting apoptosis.
Placet M, Arguin G, Molle CM, Babeu JP, Jones C, Carrier JC, Robaye B, Geha S, Boudreau F, Gendron FP.
Biochim Biophys Acta Mol Basis Dis. 2018 May;1864(5 Pt A):1539-1551.

Involvement of the coatomer protein complex I in the intracellular traffic of the delta opioid receptor.
St-Louis É, Degrandmaison J, Grastilleur S, Génier S, Blais V, Lavoie C, Parent JL, Gendron L.
Mol Cell Neurosci. 2017; 79: 53.

Gαs protein binds ubiquitin to regulate epidermal growth factor receptor endosomal sorting.
Li X, Létourneau D, Holleran B, Leduc R, Lavigne P, Lavoie C.
Proc Natl Acad Sci U S A. 2017; 114: 13477.

Transcription factor CUX1 is required for intestinal epithelial wound healing and targets the VAV2-RAC1 Signalling complex.
Latreille R, Servant R, Darsigny M, Marcoux S, Jones C, Perreault N, Boudreau F.
Biochim Biophys Acta Mol Cell Res. 2017 Dec;1864(12):2347-2355.

Expression of SOCS1 and the downstream targets of its putative tumor suppressor functions in prostate cancer.
Chevrier M, Bobbala D, Villalobos-Hernandez A, Khan MG, Ramanathan S, Saucier C, Ferbeyre G, Geha S, Ilangumaran S.
BMC Cancer. 2017; 17: 157.

Caspase-mediated proteolysis of the sorting nexin 2 disrupts retromer assembly and potentiates Met/hepatocyte growth factor receptor signaling.
Duclos CM, Champagne A, Carrier JC, Saucier C, Lavoie CL, Denault JB.
Cell Death Discov. 2017 ; 3: 16100.

SOCS1 regulates senescence and ferroptosis by modulating the expression of p53 target genes.
Saint-Germain E, Mignacca L, Vernier M, Bobbala D, Ilangumaran S, Ferbeyre G.
Aging (Albany NY). 2017; 9: 2137.

Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy.
Fujita N, Huang W, Lin TH, Groulx JF, Jean S, Nguyen J, Kuchitsu Y, Koyama-Honda I, Mizushima N, Fukuda M, Kiger AA.
Elife. 2017 Jan 7;6.

Heme Assimilation in Schizosaccharomyces pombe Requires Cell-surface-anchored Protein Shu1 and Vacuolar Transporter Abc3.
Mourer T, Normant V, Labbé S.
J Biol Chem. 2017; 292: 4898.

PACE4 Undergoes an Oncogenic Alternative Splicing Switch in Cancer.
Couture F, Sabbagh R, Kwiatkowska A, Desjardins R, Guay SP, Bouchard L, Day R.
Cancer Res. 2017; 77: 6863.

Deep transcriptome annotation enables the discovery and functional characterization of cryptic small proteins.
Samandi S, Roy AV, Delcourt V, Lucier JF, Gagnon J, Beaudoin MC, Vanderperre B, Breton MA, Motard J, Jacques JF, Brunelle M, Gagnon-Arsenault I, Fournier I, Ouangraoua A, Hunting DJ, Cohen AA, Landry CR, Scott MS, Roucou X.
Elife. 2017; 6 pii: e27860.

Attenuation of MET-mediated migration and invasion in hepatocellular carcinoma cells by SOCS1.
Gui Y, Khan MGM, Bobbala D, Dubois C, Ramanathan S, Saucier C, Ilangumaran S.
World J Gastroenterol. 2017; 23: 6639

Regulation of platelet-activating factor-mediated protein tyrosine phosphatase 1B activation by a Janus kinase 2/calpain pathway.
Hamel-Côté G, Gendron D, Rola-Pleszczynski M, Stankova J.
PLoS One. 2017; 12: e0180336.

Hypoxia-induced mobilization of NHE6 to the plasma membrane triggers endosome hyperacidification and chemoresistance.
Lucien F, Pelletier PP, Lavoie RR, Lacroix JM, Roy S, Parent JL, Arsenault D, Harper K, Dubois CM.
Nat Commun. 2017; 8: 15884.

GTPase of the Immune-Associated Nucleotide Protein 5 Regulates the Lysosomal Calcium Compartment in T Lymphocytes.
Serrano D, Ghobadi F, Boulay G, Ilangumaran S, Lavoie C, Ramanathan S.
Front Immunol. 2017; 8: 94.

Functional inhibition of chemokine receptor CCR2 by dicer-substrate-siRNA prevents pain development.
Bégin-Lavallée V, Midavaine É, Dansereau MA, Tétreault P, Longpré JM, Jacobi AM, Rose SD, Behlke MA, Beaudet N, Sarret P.
Mol Pain. 2016 Jun 15;12.

Distinct Roles for Intestinal Epithelial Cell-Specific Hdac1 and Hdac2 in the Regulation of Murine Intestinal Homeostasis.
Gonneaud A, Turgeon N, Boudreau F, Perreault N, Rivard N, Asselin C.
J Cell Physiol. 2016 Feb;231(2):436-48.

Cathepsin B promotes colorectal tumorigenesis, cell invasion, and metastasis.
Bian B, Mongrain S, Cagnol S, Langlois MJ, Boulanger J, Bernatchez G, Carrier JC, Boudreau F, Rivard N.
Mol Carcinog. 2016 May;55(5):671-87.

SHP-2 Phosphatase Prevents Colonic Inflammation by Controlling Secretory Cell Differentiation and Maintaining Host-Microbiota Homeostasis.
Coulombe G, Langlois A, De Palma G, Langlois MJ, McCarville JL, Gagné-Sanfaçon J, Perreault N, Feng GS, Bercik P, Boudreau F, Verdu EF, Rivard N.
J Cell Physiol. 2016 Nov;231(11):2529-40.

SHP-2 phosphatase contributes to KRAS-driven intestinal oncogenesis but prevents colitis-associated cancer development.
Gagné-Sansfaçon J, Coulombe G, Langlois MJ, Langlois A, Paquet M, Carrier J, Feng GS, Qu CK, Rivard N.
Oncotarget. 2016 Oct 4;7(40):65676-65695.

Gata4 is critical to maintain gut barrier function and mucosal integrity following epithelial injury.
Lepage D, Bélanger É, Jones C, Tremblay S, Allaire JM, Bruneau J, Asselin C, Perreault N, Menendez A, Gendron FP, Boudreau F.
Sci Rep. 2016 Nov 9;6:36776.

Loss of mesenchymal bone morphogenetic protein signaling leads to development of reactive stroma and initiation of the gastric neoplastic cascade.
Roy SA, Allaire JM, Ouellet C, Maloum-Rami F, Pomerleau V, Lemieux É, Babeu JP, Rousseau J, Paquet M, Garde-Granger P, Boudreau F, Perreault N.
Sci Rep. 2016 Sep 9;6:32759.

Bmp signaling in colonic mesenchyme regulates stromal microenvironment and protects from polyposis initiation.
Allaire JM, Roy SA, Ouellet C, Lemieux É, Jones C, Paquet M, Boudreau F, Perreault N.
Int J Cancer. 2016 Jun 1;138(11):2700-12.

Regulation of GPCR expression through an interaction with CCT7, a subunit of the CCT/TRiC complex.
Génier S, Degrandmaison J, Moreau P, Labrecque P, Hébert TE, Parent JL.
Mol Biol Cell. 2016 Dec 1;27(24):3800-3812. Epub 2016 Oct 5.

Platelet-Derived Growth Factor Receptor Activation Promotes the Prodestructive Invadosome-Forming Phenotype of Synoviocytes from Patients with Rheumatoid Arthritis.
Charbonneau M, Lavoie RR, Lauzier A, Harper K, McDonald PP, Dubois CM.
J Immunol. 2016 Apr 15;196(8):3264-75.

Snail Is a Critical Mediator of Invadosome Formation and Joint Degradation in Arthritis.
Lauzier A, Lavoie RR, Charbonneau M, Gouin-Boisvert B, Harper K, Dubois CM.
Am J Pathol. 2016 Feb;186(2):359-74.

Calnuc Function in Endosomal Sorting of Lysosomal Receptors.
Larkin H, Costantino S, Seaman MN, Lavoie C.
Traffic. 2016 Apr;17(4):416-32.